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Anesthesia & Analgesia: January 4, 2016 AUTHORS: Epstein, Richard H. MD, CPHIMS et al BACKGROUND: Reducing fresh gas flow (FGF) during general anesthesia reduces costs by decreasing the consumption of volatile anesthetics and attenuates their contribution to greenhouse gas pollution of the environment. The sevoflurane FGF recommendations in the Food and Drug Administration package insert […]
Read MoreBMC Anesthesiol. 2015;15(118) Authors: Xian-Xue Wang et al Background: Dexamethasone is an antiemetic alternative to ondansetron. We aimed to compare the effects of dexamethasone and ondansetron in preventing postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic surgery. Methods: We searched PubMed, Embase, Medline and Cochrane Library (from inception to July 2014) for eligible studies. The primary outcome […]
Read MoreAnesthesia & Analgesia: December 30, 2015 AUTHORS: Kamel, Ihab MD et BACKGROUND: Peripheral nerve injury is a significant perioperative problem. Intraoperative position-related neurapraxia may indicate impending peripheral nerve injury and can be detected by changes in somatosensory evoked potentials (SSEP). The purpose of this retrospective analysis of spine surgeries performed under general anesthesia with SSEP […]
Read MoreA large retrospective analysis has uncovered a previously unnoticed linear relationship between mortality and units of blood transfused, namely, that there is a 10% increase in mortality for every additional 10 units of blood transfused—what has been dubbed “the 50/50 rule.” Morbidities were also assessed. Trauma patients brought to the ER are often in hemorrhagic […]
Read MoreBMC Anesthesiol. 2015;15(112) Authors: Elke E K M Tjeertes et al Background: Obesity is generally believed to be a risk factor for the development of postoperative complications. Although being obese is associated with medical hazards, recent literature shows no convincing data to support this assumption. Moreover a paradox between body mass index and survival is described. This […]
Read MoreThe overwhelming majority of people who survive an overdose of prescription opioids continue to be prescribed opioids afterward, often by the same prescriber, according to a new study. “We found the degree of continued prescribing both surprising and concerning,” lead investigator Marc Larochelle, MD, MPH, from Boston Medical Center, in Massachusetts, told Medscape Medical News. Using […]
Read MoreThe United States Drug Enforcement Administration (DEA) issued a nationwide alert to warn the public—and law enforcement in particular—about the dangers of fentanyl and its analogues/compounds. The DEA reported that heroin abuse and fentanyl-related seizures is on the rise. Fentanyl submissions increased from 942 to 3,344 between 2013 and 2014, according to data from the […]
Read MoreIt is disturbingly common, dangerously lethal and difficult to diagnose, yet propofol-related infusion syndrome (PRIS) may be detected before it happens, given proper vigilance by anesthesiologists. Indeed, research has found a positive correlation between the duration of propofol infusion and increasing triglyceride (TG) levels, which may indicate onset of the deadly complication. “Obviously, propofol has […]
Read MoreAnesthesia & Analgesia: February 2016 – Volume 122 – Issue 2 – p 462–469 AUTHORS: Ice, Calvin J. PharmD et al BACKGROUND: The reported incidence of hypotension and bradycardia in patients receiving dexmedetomidine for sedation commonly exceeds 50%. In this study, we describe the incidence of, patient- and treatment-specific risk factors for, and clinical significance […]
Read MoreDigital subtraction angiography (DSA) has been touted as a radiologic adjunct to interventional neuraxial procedures where it is imperative to identify vascular compromise during the injection. Transforaminal epidural steroid injections (TFESI) are commonly performed interventions for treating acute and chronic radicular spine pain. We present a case of instantaneous and irreversible paraplegia following lumbar TFESI […]
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