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Authors: Timothy J. Wigmore, MA, FRCA, FFCM, FFICM FCICM et al Anesthesiology published on 11 2015. Background: Surgical resection remains the best option for long-term survival in many solid tumors. Surgery can, however, lead to tumor cell release into the circulation. Data have suggested differential effects of anesthetic agents on cancer cell growth. This retrospective analysis investigated the […]
Read MoreThe FDA has approved a nasal spray version of naloxone hydrochloride (marketed as Narcan) to stop or reverse opioid overdose. The drug was previously approved only as an injection; the new version, says the agency, is both easier for first responders to administer and eliminates the risk for needlestick contamination. The drug is indicated for […]
Read MoreAuthors: McCarthy ML et al., Ann Emerg Med 2015 Oct 13; A large trial shows that ultrasound helps with moderate or difficult anticipated IV access when lines are placed by emergency department technicians. Multiple small studies since 2005 have shown that ultrasound guidance improves success of peripheral intravenous (IV) line placement when access is difficult. These researchers […]
Read MorePatients who had emergency general surgery are at high risk for readmission within 30 days of their hospitalizations due to surgical-site infections and gastrointestinal complications, according to new research published in the Journal of the American Medical Association Surgery. Joaquim M. Havens, M.D., of Brigham and Women’s Hospital, Boston and colleagues examined factors for 30-day readmissions of […]
Read MoreAlthough opioids are frequently prescribed to treat chronic lower back pain, new research suggests these powerful medications may be less effective in some patients. A study published in the Online First edition of Anesthesiology, the official medical journal of the American Society of Anesthesiologists® (ASA®), found patients who were prescribed opioids to treat chronic lower back […]
Read MoreAuthors: Kelly A. Pollak, MD et al Anesthesiology 11 2015, Vol.123, 1133-1141. Background: The authors examined changes in the frequency of pain medicine malpractice claims and associated treatment modalities and outcomes over time. Methods: The authors analyzed trends in pain medicine claims from 1980 to 2012 in the Anesthesia Closed Claims Project database by binary logistic regression on year […]
Read MoreAuthors: Shun Kohsaka MD et al Anesthesiology published on 10 2015 Background: The authors evaluated the effect of preoperative β-blocker use on early outcomes in patients undergoing coronary artery bypass grafting (CABG) in Japan. Methods: The authors analyzed 34,980 cases of isolated CABGs, performed between 2008 and 2011, at the 333 sites recorded in the Japanese Cardiovascular Surgical Database. […]
Read MoreAuthors: Regina P. Schukro MD et al Anesthesiology published on 10 2015 Background: Among patients with chronic low back pain (CLBP), approximately 37% show signs of a neuropathic pain component (radicular pain). Treatment of this condition remains challenging. Therefore, the current study aimed to investigate the efficacy of duloxetine in the treatment of CLBP patients with neuropathic leg […]
Read MoreAuthors: Marianne Myhre MD et al Anesthesiology published on 11 2015 Background: Pregabalin is widely used perioperatively. The authors explored the effects of pregabalin, remifentanil, and their combination on experimental pain, ventilatory, and cognitive function. Methods: In a randomized, double-blinded crossover study, 12 volunteers received (1) pregabalin + placebo, (2) placebo + remifentanil, (3) pregabalin + remifentanil, and (4) […]
Read MoreAuthors: Carlo Olivieri MD, et al Anesthesiology Newly Published on 11 2015 Background: The helmet is a well-tolerated interface for noninvasive ventilation, although it is associated with poor patient–ventilator interaction. A new helmet (NH) has proven to attenuate this limitation of the standard helmet (SH) in both bench study and healthy volunteers. The authors compared a NH and […]
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