-
-
Call more information
660-596-2224 -
Anesthesiology 9 2015, Vol.123, 618-627 Authors: Massimo Cressoni MD et al Background: During mechanical ventilation, stress and strain may be locally multiplied in an inhomogeneous lung. The authors investigated whether, in healthy lungs, during high pressure/volume ventilation, injury begins at the interface of naturally inhomogeneous structures as visceral pleura, bronchi, vessels, and alveoli. The authors wished also to […]
Read MoreAnesthesiology 9 2015, Vol.123, 548-556 Authors: Matthew A. Timmins, B.Sc, et al Background: Malignant hyperthermia (MH) is triggered by reactions to anesthetics. Reports link nonanesthetic-induced MH-like reactions to a variety of disorders. The objective of the authors was to retrospectively investigate the reasons for referrals for MH testing in nonanesthetic cases and assess their phenotype. In addition, the […]
Read MoreAuthors: Douketis JD et al., N Engl J Med 2015 Aug 27; 373:823 Perioperative “bridging” anticoagulation in warfarin-treated AF patients didn’t prevent thromboembolism but did cause excess major bleeding. In the U.S., many warfarin-treated patients with atrial fibrillation (AF) who undergo elective surgery receive perioperative bridging anticoagulation, despite a paucity of evidence supporting this practice. In this […]
Read MoreAnesthesiology 9 2015, Vol.123, 542-547 Authors: Martin Neukirchen NM et al Background: Impaired cardiac repolarization, indicated by prolonged QT interval, may cause critical ventricular arrhythmias. Many anesthetics increase the QT interval by blockade of rapidly acting potassium rectifier channels. Although xenon does not affect these channels in isolated cardiomyocytes, the authors hypothesized that xenon increases the QT […]
Read MoreAnesthesiology 9 2015, Vol.123, 535-541 Authors: David B. Auyong MD et al Background: Despite ultrasound guidance for central line placement, complications persist, as exact needle location is often difficult to confirm with standard two-dimension ultrasound. A novel real-time needle guidance technology has recently become available (eZono, Germany) that tracks the needle during insertion. This randomized, blinded, crossover study examined […]
Read MoreAuthors: Appelboam A et al., Lancet 2015 Aug 24; A simple modification in the Valsalva maneuver dramatically increased its effectiveness. The Valsalva maneuver is recommended first-line treatment for stable patients with supraventricular tachycardia, although it is successful in only a minority of patients. These authors tested whether a modified Valsalva maneuver can improve cardioversion rates. In a […]
Read MoreAnesthesiology 10 2015, Vol.123, 810-819 Authors: Creed M. Stary, MD, PhD et al Background: Isoflurane induces cell death in neurons undergoing synaptogenesis via increased production of pro-brain–derived neurotrophic factor (proBDNF) and activation of postsynaptic p75 neurotrophin receptor (p75NTR). Astrocytes express p75NTR, but their role in neuronal p75NTR-mediated cell death remains unclear. The authors investigated whether astrocytes have the capacity […]
Read MoreAnesthesiology 9 2015, Vol.123, 524-534 Authors: Chris H. Martini MD et al ; Background: A novel multidimensional index of nociception, the nociception level (NoL) index, derived from the nonlinear composite of heart rate (HR), HR variability, amplitude of the photoplethysmogram, skin conductance, fluctuations in skin conductance, and their time derivatives, was used to assess nociception during anesthesia. Methods: Seventy-two […]
Read MoreAnesthesiology 9 2015, Vol.123, 515-523 Authors: Louise Y. Sun MD, PhD, et al Background: Intraoperative hypotension (IOH) may be associated with postoperative acute kidney injury (AKI), but the duration of hypotension for triggering harm is unclear. The authors investigated the association between varying periods of IOH with mean arterial pressure (MAP) less than 55, less than 60, and […]
Read MoreAnesthesiology 9 2015, Vol.123, 507-514 Authors: Eric C. Sun MD, PhD et al Background: Markets for physician services are becoming increasingly concentrated, with many areas being dominated by a few groups. Antitrust authorities are concerned that increasing concentration will lead to inappropriately high payments for physician services from private insurers. The authors examined the association between market concentration […]
Read More