Month: July 2015

Uncategorized Published - 24 July, 2015    By - Dr Clemens
Impaired Sleep Linked to Lower Pain Tolerance

People with insomnia and other sleep problems have increased sensitivity to pain, according to a study published in the journal Pain. The effect on pain tolerance appears strongest in people who suffer from both insomnia and chronic pain, who may benefit from treatments targeting both conditions. The study included more than 10,400 adults from a […]

Read More
Uncategorized Published - 23 July, 2015    By - Dr Clemens
The Contribution of Differential Opioid Responsiveness to Identification of Opioid Risk in Chronic Pain Patients

J Pain 2015 Jul;16(7):666-75. Authors: Bruehl S et al Abstract The Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) predicts increased risk of opioid misuse in chronic pain patients. We evaluated whether higher SOAPP-R scores are associated with greater opioid reinforcing properties, potentially contributing to their predictive utility. Across 2 counterbalanced laboratory sessions, 55 chronic low […]

Read More
Uncategorized Published - 23 July, 2015    By - Dr Clemens
Effectiveness of transcranial direct current stimulation preceding cognitive behavioural management for chronic low back pain: sham controlled double blinded randomised controlled trial

BMJ. April 2015; 350: h1640. Authors: Kerstin Luedtke postdoctoral researcher, et al Objective To evaluate the effectiveness of transcranial direct current stimulation alone and in combination with cognitive behavioural management in patients with non-specific chronic low back pain. Design Double blind parallel group randomised controlled trial with six months’ follow-up conducted May 2011-March 2013. Participants, physiotherapists, assessors, and […]

Read More
Uncategorized Published - 23 July, 2015    By - Dr Clemens
Safety of deep sedation in young children with sickle cell disease: a retrospective cohort study

J Pediatr 2015 May;166(5):1226-32 Authors: Belmont AP et al OBJECTIVE: To assess the rates and types of complications associated with deep sedation in children with sickle cell disease (SCD) and to explore potential risk factors. STUDY DESIGN: This was a retrospective cohort study of children with SCD and a comparison group of children without SCD who underwent […]

Read More
Uncategorized Published - 23 July, 2015    By - Dr Clemens
Neurocognitive dysfunction risk alleviation with the use of dexmedetomidine in perioperative conditions or as ICU sedation: a meta-analysis

Medicine (Baltimore) 2015 Apr;94(14):e597 Authors: Li B et al Abstract Many studies have reported the beneficial effects of dexmedetomidine on postoperative neurocognitive function but overall evidence is not as clear. We examined this conundrum by meta-analyzing studies that used dexmedetomidine in perioperative conditions or as intensive care unit (ICU) sedation and utilized reliable neurocognitive assessment tests. The […]

Read More
Uncategorized Published - 23 July, 2015    By - Dr Clemens
FDA OKs First Patient-Controlled Patch for Postop Pain

The US Food and Drug Administration has approved fentanyl iontophoretic transdermal system (Ionsys, The Medicines Co), the first needle-free, patient-controlled, preprogrammed fentanyl delivery system for management of acute postoperative pain in adults requiring opioid analgesia in the hospital, according to a company news release. Ionsys is a “novel alternative” to traditional intravenous patient-controlled analgesia that uses […]

Read More
Uncategorized Published - 22 July, 2015    By - Dr Clemens
Comparison of the efficacy and safety of sedation between dexmedetomidine-remifentanil and propofol-remifentanil during endoscopic submucosal dissection

World J Gastroenterol 2015 Mar 28;21(12):3671-8. Authors: Kim N et al AIM: To compare the efficacy and safety of sedation protocols for endoscopic submucosal dissection (ESD) between dexmedetomidine-remifentanil and propofol-remifentanil. METHODS: Fifty-nine patients scheduled for ESD were randomly allocated into a dexmedetomidine-remifentanil (DR) group or a propofol-remifentanil (PR) group. To control patient anxiety, dexmedetomidine or propofol was […]

Read More
Uncategorized Published - 22 July, 2015    By - Dr Clemens
Impact of inhalation vs. intravenous anaesthesia on autonomic nerves and internal anal sphincter tone

Acta Anaesthesiol Scand 2015 Apr 21 Authors: Heid F et al BACKGROUND: Pelvic intraoperative neuromonitoring (pIONM) aims to identify and spare the autonomic nerves and maintain patients’ quality of life. The effect of anaesthetic agents on the pIONM signal is unknown; therefore, the aim of the present study was to compare the influences of inhalation anaesthesia (IA) […]

Read More
Uncategorized Published - 22 July, 2015    By - Dr Clemens
The effect of two different doses of remifentanil on postoperative pain and opioid consumption after cardiac surgery – a randomized controlled trial

Acta Anaesthesiol Scand 2015 Apr 21. Authors: Florkiewicz P et al BACKGROUND: Remifentanil, an ultra-short-acting opioid, provides intensive analgesia without prolonged respiratory depression and is widely used in cardiac surgery. Diminished dosing may also offer stable hemodynamics, even during sternotomy and sternal retraction. However, increased postoperative pain and induced opioid tolerance after remifentanil dosing during abdominal surgery […]

Read More
Uncategorized Published - 22 July, 2015    By - Dr Clemens
A Single Consent for Serial Anesthetics in Burn Surgery

Anesthesia & Analgesia: July 2015- Volume 121-Issue 1- p 219-222 Authors: Fahy, Brenda G. MD et al Obtaining anesthesia informed consent for a series of repetitive debridements in burn-injured patients requires a significant time investment for anesthesiologists and patient families. A single consent form was introduced that covered multiple related anesthetics in burn patients. The […]

Read More