Published in Surg Laparosc Endosc Percutan Tech. 2014 Jun 6
Authors: Zhao YJ et al
We aim to assess efficacy and safety of remifentanil or sulfentanyl combined with propofol during painless gastroscopic examination in patients. In this study, 270 patients were randomly divided into 3 groups: propofol was given only in group P; propofol and remifentanil in group PR; propofol and sulfentanyl in group PS during the gastroscopic examination.
Efficiency of group P was significantly lower than that of group PR and PS (P less than 0.01). Efficiency of group PR was lower than that of group PS (P less than 0.05). Incidence of chest wall rigidity and oxygen desaturation in group PR were higher than group P and PS (P less than 0.05), whereas there was no difference between groups P and PS (P greater than 0.05).
Propofol combined with remifentanil could provide satisfying anesthesia and more respiratory depression, whereas sulfentanyl at equivalent dose combined with propofol could also provide with satisfying anesthesia and less respiratory depression.
Combined sufentanyl with propofol would be an effective anesthesia technique in the daytime procedure.