Effects of stellate ganglion block on cardiovascular reaction and heart rate variability in elderly patients during anesthesia induction and endotracheal intubation.

PUBLISHED:
J Clin Anesth. 2015 Mar;27(2):140-5

Authors: Chen YQ et al

STUDY OBJECTIVE:
To investigate the effects of stellate ganglion block (SGB) on cardiovascular response and heart rate (HR) variability in elderly patients during anesthesia induction and endotracheal intubation.

DESIGN:
A randomized, double-blinded, and placebo-controlled study.

SETTING:
University-affiliated teaching hospital.

PARTICIPANTS:
Eighty elderly patients (American Society of Anesthesiologists grades I and II) receiving elective surgery during general anesthesia.

INTERVENTIONS:
Right stellate ganglion injection (SGB) was performed in all patients using 10 mL of 1% lidocaine or normal saline.

MEASUREMENTS:
Systolic blood pressure (BP), diastolic BP, HR, and calculated rate pressure product. HR variability at the following time points: conscious status before induction (T0); immediately before intubation (T1); immediately after intubation (T2); and 1, 3, and 5 minutes postintubation (T3, T4, and T5).

MAIN RESULTS:
No significant differences in BP and HR were observed between the 2 groups. Rate pressure product values significantly increased in the control group compared with baseline and SGB group values. Low-frequency power (LF) and LF/high-frequency power (HF) significantly increased, and HF and normalized units of HF significantly decreased in the control group compared with baseline values. LF, normalized units of LF, and LF/HF in the SGB group significantly decreased compared with those of the control group.

CONCLUSION:
SGB protects the myocardium and effectively suppresses stress responses during anesthesia induction and tracheal intubation in elderly patients.