FDA: Not Enough Data to Make New Recommendations on Pain Meds During Pregnancy

Pregnant women should carefully consider whether or not to take pain medication, the FDA advises. However, the agency says that it cannot make any new recommendations on pain medication during pregnancy because available data are too limited. The agency reviewed available data in response to concerns about the safety of using either over-the-counter (e.g., acetaminophen, […]

Persistent paralysis after spinal anesthesia for cesarean delivery

Published in Journal of Clinical Anesthesia (JCA) (Nov 2014) Authors: Zaphiratos V et al Anterior spinal artery syndrome has rarely been reported as a cause of permanent neurologic complications after neuraxial anesthesia in obstetric patients. A parturient developed anterior spinal artery syndrome after spinal anesthesia for cesarean delivery. A healthy 32-year-old parturient presented at 41(2/7) […]

Calibrated versus uncalibrated arterial pressure waveform analysis in monitoring cardiac output with transpulmonary thermodilution in patients with severe sepsis and septic shock: An observational study

Published in European Journal of Anaesthesiology January 2015 – Volume 32 – Issue 1 – p 5–12 Authors: Slagt et al BACKGROUND: Cardiac output (CO) measurement is often required in critically ill patients. The performances of newer, less invasive techniques require evaluation in patients with severe sepsis and septic shock. OBJECTIVES: To compare calibrated arterial […]

How Many Cycles of OnabotulinumtoxinA for Chronic Migraine?

Authors: Silberstein SD et al., J Neurol Neurosurg Psychiatry 2014 Dec 12; Most chronic migraineurs who ultimately respond to onabotulinumtoxinA do so with the first cycle, but a proportion of initial nonresponders may respond to a second or third cycle. In this manufacturer-funded study, researchers examined how many chronic migraineurs who do not respond to the first […]

Little Evidence to Guide Opioid Use for Chronic Pain Management

There is little evidence that patients with chronic pain who receive long-term opioid treatment have improved function, enhanced quality of life, or diminished pain, according to a position paper in the Annals of Internal Medicine. Based on a National Institutes of Health workshop on the role of opioids for pain management, a panel recommends that “in […]

Pediatric airway anatomy may not be what we thought: implications for clinical practice and the use of cuffed endotracheal tubes

Published in Paediatric Anaesthesia (Sep 2014) Authors: Tobias J et al One of the long held tenets of pediatric anesthesia has been the notion that the pediatric airway is conical shape with the narrowest area being the cricoid region. However, recent studies using radiologic imaging techniques (magnetic resonance imaging and computed tomography) or direct bronchoscopic […]

Ketamine peritonsillar infiltration during tonsillectomy in pediatric patients: An updated meta-analysis

Published in International Journal of Pediatric Otorhinolaryngology 78 (10), 1735-41 (Oct 2014) Authors: Tong Y et al OBJECTIVES Peri-operative ketamine peritonsillar infiltration in children can reduce the incidence of postoperative nausea and vomiting (PONV), but its postoperative analgesic time is short. A previous meta-analysis in 2011 was inconclusive due to insufficient data. Consequently, we updated […]

Comparative Effects of Morning vs Evening Dosing of Extended-Release Hydromorphone on Sleep Physiology in Patients with Low Back Pain: A Pilot Study

Published in Pain Medicine (Oct 2014) Authors: Webster L et al OBJECTIVE To investigate effects of extended-release (ER) hydromorphone dosing time (morning, QAM; evening, QPM) on sleep physiology in patients with chronic low back pain. DESIGN Randomized, double-blind, placebo-controlled, crossover trial. SETTING Clinical research site. PATIENTS Fifteen patients with moderate-to-severe chronic low back pain requiring […]

11 Tips for Better Opioid Prescribing

Editor’s Note: As part of its effort to facilitate responsible opioid prescribing, the American Academy of Addiction Psychiatry(AAAP) hosts a listserv where clinicians can submit clinical questions and receive responses from a rotating panel of pain experts. In conjunction with the AAAP selected 10 of the most common questions or topics related to opioid use […]

Majority still supports single-payer option, poll finds

More than five years after the single-payer system was scrapped from ObamaCare policy debates, just over 50 percent of people say they still support the idea, including one-quarter of Republicans, according to a new poll. The single-payer option – also known as Medicare for all – would create a new, government-run insurance program to replace […]