Authors: Susie Yoon, M.D., Ph.D. et al Anesthesiology May 2024, Vol. 140, 920–934. Background Mechanical power (MP), the rate of mechanical energy (ME) delivery, is a recently introduced unifying ventilator parameter consisting of tidal volume, airway pressures, and respiratory rates, which predicts pulmonary complications in several clinical contexts. However, ME has not been previously studied in […]
Modified Thermodilution for Simultaneous Cardiac Output and Recirculation Assessment in Veno-venous Extracorporeal Membrane Oxygenation
Autors: David Berger, M.D. et al Anesthesiology May 2024, Vol. 140, 1002–1015. Background Thermodilution is unreliable in veno-venous extracorporeal membrane oxygenation (VV-ECMO). Systemic oxygenation depends on recirculation fractions and ratios of extracorporeal membrane oxygenation (ECMO) flow to cardiac output. In a prospective in vitro simulation, this study assessed the diagnostic accuracy of a modified thermodilution technique for recirculation […]
State-related Electroencephalography Microstate Complexity during Propofol- and Esketamine-induced Unconsciousness
Authors: Zhenhu Liang, Ph.D. et al Anesthesiology May 2024, Vol. 140, 935–949. Background Identifying the state-related “neural correlates of consciousness” for anesthetics-induced unconsciousness is challenging. Spatiotemporal complexity is a promising tool for investigating consciousness. The authors hypothesized that spatiotemporal complexity may serve as a state-related but not drug-related electroencephalography (EEG) indicator during an unconscious state induced […]
5 things anyone opening an ASC should know
Author: Paige Haeffele Becker’s ASC Review In the ever-changing healthcare market, starting a new venture can feel like a big risk. Becker’s connected with Vladimir Sinkov, MD, the founder and CEO of Sinkov Spine Center in Las Vegas, to learn valuable tips that anyone wanting to break into the ASC market should know. Question: What advice […]
Nerve injury triggers time-dependent activation of the locus coeruleus, influencing spontaneous pain-like behavior in rats
Authors: Irene Suárez-Pereira, Ph.D. et al Anesthesiology April 2024. Background Dynamic changes in neuronal activity and in noradrenergic locus coeruleus (LC) projections have been proposed during the transition from acute to chronic pain. Thus, we explored the cellular cFos activity of the LC and its projections, in conjunction with spontaneous pain-like behavior in neuropathic rats. […]
Science, Medicine, and the Anesthesiologist
Anesthesiology May 2024, Vol. 140, A13–A15. An electroencephalographic signature predicts craving for methamphetamine. Cell Rep Med 2024; 5:101347. PMID: 38151021. Article Selection: Jamie Sleigh, M.D. Image: Adobe Stock. The subjective drug craving is the core driver of methamphetamine use disorder and its relapse rate. There are no reliable biomarkers of this, but it is possible that […]
Addressing Patient Concerns with Blood Transfusion from Donors Vaccinated Against COVID-19
Authors: Katherine T. Forkin, M.D. et al Anesthesiology May 2024, Vol. 140, 1020–1025. Clinicians across the country have experienced a rise in patient requests to avoid blood products from donors vaccinated against SARS-CoV-2 (referred hereafter using the more commonly used disease term COVID-19). Patient concerns regarding blood transfusions from donors vaccinated against COVID-19 are often centered […]
Science, Medicine, and the Anesthesiologist
Anesthesiology May 2024, Vol. 140, A13–A15. Skin antisepsis before surgical fixation of extremity fractures. N Engl J Med 2024; 390:409–20. PMID: 38294973. Article Selection: Martin J. London, M.D. Image: Adobe Stock. Conflicting results have been reported with respect to the type of skin antisepsis used prior to surgical incision to repair limb fractures with regard to […]
Science, Medicine, and the Anesthesiologist
Anesthesiology May 2024, Vol. 140, A13–A15. Trial of selective early treatment of patent ductus arteriosus with ibuprofen. N Engl J Med 2024; 390:314–25. PMID: 38265644. Article Selection: Martin J. London, M.D. Image: Adobe Stock. The presence of patent ductus arteriosus in preterm infants beyond 3 days of age, particularly 1.5 mm or larger in diameter, is associated […]
Science, Medicine, and the Anesthesiologist
Anesthesiology May 2024, Vol. 140, A13–A15. Transcatheter aortic-valve replacement in low-risk patients at five years. N Engl J Med 2023; 389:1949–60. PMID: 37874020. Article Selection: Martin J. London, M.D. Image: Adobe Stock. An industry-sponsored randomized study of outcome of transcatheter aortic valve replacement (TAVR) versus surgical replacement (Edwards Lifesciences PARTNER trial; SAPIEN-3 valve) in patients with severe, symptomatic […]