Technology in Anesthesiology

In a pioneering study, researchers implanted a transparent window in a patient’s skull and used functional ultrasound imaging (fUSI) to gather high-resolution brain data. This novel method, applied for the first time in an awake, behaving human performing tasks, offers significant potential for noninvasive brain monitoring and clinical research. The patient, who had suffered a traumatic brain injury, had part of his skull removed and later replaced with a custom transparent implant designed for this study. Prior to the implant surgery, the team optimized fUSI parameters using both phantom devices and animal models. They then collected fUSI data while the patient performed tasks, such as solving puzzles and playing the guitar, before and after implant installation. The clear window allowed effective measurement of brain activity, despite some reduction in data fidelity. fUSI promises higher resolution than current methods like fMRI and intracranial EEG, without the need for invasive electrodes and at a lower cost. Additionally, the transparent window aids in monitoring for complications like blood clots postsurgery. This technique could revolutionize patient monitoring, provide insights into neurological conditions, and improve understanding of brain functions.

Source: asamonitor.pub/3yWdV4a