Anesthesia Experts

Omega-3 Polyunsaturated Fatty Acids Are Associated with Healthy Aging

by Leave a Comment

I thought it was interesting so I wanted to share it with our readers.

Paul S. Mueller, MD, MPH, FACP reviewing Lai HTM et al. 

BMJ 2018 Oct 17

Plasma levels of seafood-derived long-chain ω-3s in elders predicted risk for various adverse conditions.

Although consuming long-chain ω-3 polyunsaturated fatty acids (PUFAs) has favorable physiological effects (e.g., on endothelial function), the relation between plasma PUFAs and healthy aging is unknown. In this prospective cohort study, researchers determined the longitudinal association between serial measures of summed and individual plasma PUFAs (i.e., eicosapentaenoic, docosapentaenoic, and docosahexaenoic acid) and α-linolenic acid and healthy aging.

Participants were 2622 elders (mean age, 74) with healthy aging at baseline. Healthy aging was defined as absence of cardiovascular disease, cancer, lung disease, severe chronic kidney disease, and cognitive and physical dysfunction. Plasma PUFA levels were measured three times during the study period (1992–2015), and participants were classified into quintiles based on their plasma PUFA concentrations. During the study, 89% of participants experienced unhealthy aging. In an analysis that was adjusted for multiple variables, risk for unhealthy aging was 18% lower in participants in the highest PUFA quintile compared with those in the lowest PUFA quintile. A significant dose-response trend was observed. Assessed individually, higher intake of eicosapentaenoic and docosapentaenoic acid (but not docosahexaenoic acid or α-linolenic acid) was associated with lower risk for unhealthy aging.

COMMENT

Higher plasma levels of PUFAs, especially seafood-derived eicosapentaenoic acid and endogenous and seafood-derived docosapentaenoic acid, were associated with higher likelihood of healthy aging. This study is unique in that actual plasma levels, not dietary intake histories, were used. However, given the study design, causality could not be established, residual confounding was possible, and the results might not be generalizable to younger people. Nonetheless, the results support guidelines for increased consumption of fish.

Leave a Reply

Call (660) 596-2224
What people thought about us

Testimonials

“As Director of Surgical Services Departments there has been considerable changes have occurred in my department and Anesthesia Experts has always risen to meet our demands of our facility. They have been very pro-active in meeting the increase volumes allowing us to keep our surgeons and patients very satisfied with our services.”

AR BSN 346 beds AL   

“Before AE took over the anesthesia department was described by the surgeons as the worst in the history of our hospital. The prior management company was having a cancelled surgery per day. I am happy to report there has not been one since they have taken over the department. Additionally we have seen a 905 reduction if requested preop
lab tests. The anesthesia department is now the very best hospital department in our entire facility.”

DS CEO 272 beds MS   

“Anesthesia Experts has provided consistent anesthesia providers who display a high degree of integrity, responsibility and professionalism. They have become a more valuable part of our facility and community.”

LR CEO 150 beds TX   

“Even though they are physically located 1000 miles away Anesthesia Experts just does not provide great anesthesia coverage they personally engage surgeons to increase their business. Last year my surgical volume rose by 24% and we are currently 50% ahead of last year and all of that growth is organic.”

JE FACHE CEO AL 92 bed hospital   

“Anesthesia Experts is more responsive than anyone I have dealt with. They are available by phone whenever needed and will be on site for any need or request and has been on site to address issues before we can make the request.”

SW CEO 25 beds NM   

“While problems are extremely rare when they do occur Anesthesia Experts quickly and professionally implements a solution. Our surgical volume has grown over 100 cases per month and now our GI docs want to perform all of their endoscopies in our hospital instead of their GI lab that they own!”

SP CEO 346 beds AL   

“Our anesthesia department was a thorn in my side that kept me awake at night. Anesthesia Experts swept in and brought order to our mess and our department was quickly redirected.”

JAM CNO AL 89 bed hospital   

Add a Testimonial

Verification Captcha