Anesthesia Experts

Inverse Relation Between Cardiovascular Fitness and All-Cause Mortality

by Leave a Comment

I thought this was interesting so I wanted to include it for our readers.

Authors: Mandsager K et al. 

JAMA Netw 2018 Oct 

Life expectancy increases as aerobic fitness improves with no upper limit of benefit at any age.

The generally accepted inverse relation between cardiovascular fitness and adverse cardiovascular events and all-cause mortality has been challenged recently by reports that suggest a possible U-shaped dose-response association, in which extreme exercise and fitness is associated with excess mortality risk due to myocardial fibrosis, atrial fibrillation, and coronary artery calcification. This retrospective cohort study overcame the limitations of many studies in which self-reported exercise patterns were used.

Cleveland Clinic researchers identified 122,000 patients (mean age, 53) who were referred for symptom-limited exercise treadmill testing. According to peak achieved metabolic equivalents (METs; similar to maximal oxygen uptake), patients were stratified into five cardiorespiratory-fitness (CRF) groups: low, below average, above average, high, and elite. During median follow-up of 8 years, researchers noted an inverse relation between level of CRF and all-cause mortality across all performance levels and through age >70. For example, mortality hazard ratios (HRs) were 1.3 for high vs. elite CRF, 1.8 for above-average vs. elite CRF, and 1.4 for below-average vs. above-average CRF. Hazard ratios were adjusted for traditional cardiovascular risk factors.

COMMENT

These data are reassuring that, with regard to mortality, one can exercise safely at an “elite” level throughout life. But those who aren’t interested in achieving (or able to achieve) elite levels still will derive mortality benefits when they improve their cardiorespiratory fitness.

Leave a Reply

Call (660) 596-2224
What people thought about us

Testimonials

“As Director of Surgical Services Departments there has been considerable changes have occurred in my department and Anesthesia Experts has always risen to meet our demands of our facility. They have been very pro-active in meeting the increase volumes allowing us to keep our surgeons and patients very satisfied with our services.”

AR BSN 346 beds AL   

“Before AE took over the anesthesia department was described by the surgeons as the worst in the history of our hospital. The prior management company was having a cancelled surgery per day. I am happy to report there has not been one since they have taken over the department. Additionally we have seen a 905 reduction if requested preop
lab tests. The anesthesia department is now the very best hospital department in our entire facility.”

DS CEO 272 beds MS   

“Anesthesia Experts has provided consistent anesthesia providers who display a high degree of integrity, responsibility and professionalism. They have become a more valuable part of our facility and community.”

LR CEO 150 beds TX   

“Even though they are physically located 1000 miles away Anesthesia Experts just does not provide great anesthesia coverage they personally engage surgeons to increase their business. Last year my surgical volume rose by 24% and we are currently 50% ahead of last year and all of that growth is organic.”

JE FACHE CEO AL 92 bed hospital   

“Anesthesia Experts is more responsive than anyone I have dealt with. They are available by phone whenever needed and will be on site for any need or request and has been on site to address issues before we can make the request.”

SW CEO 25 beds NM   

“While problems are extremely rare when they do occur Anesthesia Experts quickly and professionally implements a solution. Our surgical volume has grown over 100 cases per month and now our GI docs want to perform all of their endoscopies in our hospital instead of their GI lab that they own!”

SP CEO 346 beds AL   

“Our anesthesia department was a thorn in my side that kept me awake at night. Anesthesia Experts swept in and brought order to our mess and our department was quickly redirected.”

JAM CNO AL 89 bed hospital   

Add a Testimonial

Verification Captcha