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Uncategorized Published - 24 July, 2019    By - Dr Clemens
Validation of a Second-Generation Near-Infrared Spectroscopy Monitor in Children With Congenital Heart Disease

AUTHORS: Nasr, Viviane G. MD et al Anesthesia & Analgesia: April 2019 – Volume 128 – Issue 4 – p 661-668 BACKGROUND: Cerebral oximetry using near-infrared spectroscopy is a noninvasive optical technology to detect cerebral hypoxia-ischemia and develop interventions to prevent and ameliorate hypoxic brain injury. Cerebral oximeters are calibrated and validated by comparison of the […]

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Uncategorized Published - 23 July, 2019    By - Dr Clemens
Prolonged Duration Local Anesthesia by Combined Delivery of Capsaicin- and Tetrodotoxin-Loaded Liposomes

AUTHORS: Shomorony, Andre BS et al Anesthesia & Analgesia: March 2019 BACKGROUND: Capsaicin, the active component of chili peppers, can produce sensory-selective peripheral nerve blockade. Coadministration of capsaicin and tetrodotoxin, a site-1 sodium channel blocker, can achieve a synergistic effect on duration of nerve blocks. However, capsaicin can be neurotoxic, and tetrodotoxin can cause systemic toxicity. […]

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Uncategorized Published - 23 July, 2019    By - Dr Clemens
Comparison of Programmed Intermittent Epidural Boluses With Continuous Epidural Infusion for the Maintenance of Labor Analgesia

AUTHORS: Ojo, Oluremi A. BS et al Anesthesia & Analgesia: March 2019 BACKGROUND: Programmed intermittent epidural boluses may improve the spread of local anesthetics compared to continuous epidural infusion, improving labor analgesia and obstetric outcomes. However, there are limited data from studies using commercially available pumps capable of coadministering programmed intermittent epidural boluses or continuous epidural infusion […]

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Uncategorized Published - 23 July, 2019    By - Dr Clemens
A Preoperative Cognitive Screening Test Predicts Increased Length of Stay in a Frail Population

AUTHORS: O’Reilly-Shah, Vikas N. MD, PhD et al Anesthesia & Analgesia: March 2019 BACKGROUND: Frailty is associated with adverse perioperative outcomes including major morbidity, mortality, and increased length of stay. We sought to elucidate the role that a preoperatively assessed Mini-Cog can play in assessing the risk of adverse perioperative outcomes in a population at high […]

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Uncategorized Published - 23 July, 2019    By - Dr Clemens
Effect of Dynamic Versus Stylet-Guided Intubation on First-Attempt Success in Difficult Airways Undergoing Glidescope Laryngoscopy

AUTHORS: Mazzinari, Guido MD, MSc, PhD et al Anesthesia & Analgesia: June 2019 – Volume 128 – Issue 6 – p 1264-1271 BACKGROUND: Tracheal intubation failure in patients with difficult airway is still not uncommon. While videolaryngoscopes such as the Glidescope offer better glottic vision due to an acute-angled blade, this advantage does not always lead […]

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