Conclusions: Automated anesthetic management using the combination of three controllers outperforms manual control and may have an impact on delayed neurocognitive recovery. However, given the study design, it is not possible to determine the relative contribution of each controller on the cognition score.
What We Already Know about This Topic:
Recommendations for anesthetic care are often difficult to implement in the intraoperative setting because of the requirement for continuous attention
What This Article Tells Us That Is New:
Closed-loop, automated management of anesthetic, analgesic, fluid, and ventilation parameters was superior to manual control and might influence postoperative outcomes