AUTHORS: Elsharkawy, Hesham MD, MBA, MSc, FASA et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 1138-1145 BACKGROUND:  Epidural block are often used for analgesia after open nephrectomy surgery. Subcostal anterior quadratus lumborum block may be an alternative. We therefore tested the hypothesis that the continuous subcostal anterior quadratus lumborum […]

Authors: Michael L. McManus, M.D., M.P.H. et al Anesthesiology June 2021, Vol. 134, 852–861. Background In 2015, the American College of Surgeons began its Children’s Surgery Verification Quality Improvement Program, promulgating standards intended to promote regionalization and improve pediatric surgical care. It was hypothesized that pediatric surgical care was already highly regionalized and concentrated before […]

AUTHORS: Yang, Chen MD et al Anesthesia & Analgesia: March 2021 BACKGROUND: Intraoperative hypothermia is a common complication after neuraxial block in cesarean delivery. At least 1 animal study has found that carbohydrate loading can maintain the body temperature of rats during general anesthesia, but it is unclear whether carbohydrate loading is beneficial for body temperature […]

AUTHORS: Chanthima, Phuriphong MD et al Anesthesia & Analgesia: March 2021 BACKGROUND: Transfusion of citrated blood products may worsen resuscitation-induced hypocalcemia and trauma outcomes, suggesting the need for protocolized early calcium replacement in major trauma. However, the dynamics of ionized calcium during hemostatic resuscitation of severe injury are not well studied. We determined the frequency of […]

AUTHORS: Jin, Zhaosheng MBBS et al Anesthesia & Analgesia: February 2021 BACKGROUND: Pain is one of the most common adverse events after surgery. Regional anesthesia techniques are effective for pain control but have limited duration of action. Liposomal bupivacaine is a long-acting formulation of bupivacaine. We conduct this systematic review to assess whether liposomal bupivacaine may […]

Authors: Jennifer J. Lee, M.D. et al  Anesthesiology June 2021, Vol. 134, 845–851. Background The current American Society of Anesthesiologists fasting guideline for formula-fed infants in the periprocedural setting is 6 h. Prolonged fasting in very young infants is associated with an increased risk for hypoglycemia and dehydration as well as patient discomfort and patient/parental […]

Authors: Alexandre Joosten, M.D., Ph.D. et al Anesthesiology May 2021. Background Individualized hemodynamic management during surgery relies on accurate titration of vasopressors and fluids. In this context, computer systems have been developed to assist anesthesia providers in delivering these interventions. This study tested the hypothesis that computer-assisted individualized hemodynamic management could reduce intraoperative hypotension in […]

Authors: Jason Chui, M.B.Ch.B., M.Sc., F.A.N.Z.C.A., F.H.K.C.A., F.H.K.A.M. et al Anesthesiology April 2021. Background Evoked potential monitoring is believed to prevent neurologic injury in various surgical settings; however, its clinical effect has not been scrutinized. It was hypothesized that an automated nerve monitor can minimize intraoperative nerve injury and thereby improve clinical outcomes in patients […]

Authors: Kristian-Christos Ngamsri, M.D. et al Anesthesiology April 2021 Background Sepsis is one of the leading causes of mortality in intensive care units, and sedation in the intensive care unit during sepsis is usually performed intravenously. The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in […]

Authors: Wenling Zhao, M.D. et al Anesthesiology May 2021. Background Isoflurane can induce anterograde amnesia. Hippocampal ripples are high-frequency oscillatory events occurring in the local field potentials of cornu ammonis 1 involved in memory processes. The authors hypothesized that isoflurane suppresses hippocampal ripples at a subanesthetic concentration by modulating the excitability of cornu ammonis 1 […]